New Zealand Datasheet Name of Medicine Omeprazole Infusion 40 mg
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چکیده
Site and mechanism of action Omeprazole is a weak base and is concentrated and converted to the active form in the highly acidic environment of the intracellular canaliculi within the parietal cell, where it inhibits the enzyme H+, K+-ATPase, the acid pump. This effect on the final step of the gastric acid formation process is dose-dependent and provides for highly effective inhibition of both basal acid secretion and stimulated acid secretion, irrespective of the stimulus.
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New Zealand Datasheet 1 PRODUCT NAME Dr Reddy’s Omeprazole 2 QUALITATIVE AND QUANTITATIVE COMPOSITION
For patients with swallowing difficulties the capsule can be opened and the contents swallowed directly with half a glass of liquid or after mixing the contents in a slightly acidic fluid e.g. fruit juice, yoghurt or in non carbonated water. The dispersion should be taken immediately or within 30 minutes. Alternatively patients can suck the capsule and swallow the pellets with liquid. The pelle...
متن کاملThe Effect of Two Different Doses of Omeprazole on Gastric pH in I.C.U. Patients
About 1.5-6 % of the patients with gastric and duodenal erosions admitted to I.C.U. are prone to gastrointestinal (G.I.) bleeding with its ensuing complications. Routine prophylaxis with H2-blockers and anti-acid has been used in these high risk patients for decades.In this study we evaluated the effect of P.O omeprazole, a potent acid inhibitor with prolong effects on gastric pH. Patients wit...
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تاریخ انتشار 2015